Spyre Therapeutics Inc. (SYRE)

NASDAQ: SYRE · IEX Real-Time Price · USD
21.52
+1.02 (4.98%)
Dec 29, 2023, 4:00 PM EST - Market closed
4.98%
Market Cap 87.10M
Revenue (ttm) 1.05M
Net Income (ttm) -294.43M
Shares Out 4.29M
EPS (ttm) -75.59
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 111,015
Open 20.50
Previous Close 20.50
Day's Range 19.83 - 22.00
52-Week Range 2.66 - 24.00
Beta n/a
Analysts Strong Buy
Price Target 30.00 (+39.41%)
Earnings Date Feb 29, 2024

About SYRE

Spyre Therapeutics, Inc., a biotechnology company, focuses on advancing a pipeline of antibody therapeutics for the treatment of inflammatory bowel disease by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. The company's pipeline includes extended half-life antibodies targeting a4ß7, TL1A, and IL-23. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. Spyre Therapeutics, Inc. was founded in 20... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 7, 2016
Employees 69
Stock Exchange NASDAQ
Ticker Symbol SYRE
Full Company Profile

Financial Performance

In 2022, SYRE's revenue was $2.33 million, a decrease of -87.57% compared to the previous year's $18.74 million. Losses were -$83.82 million, 27.4% more than in 2021.

Financial Statements

Analyst Forecast

According to 4 analysts, the average rating for SYRE stock is "Strong Buy." The 12-month stock price forecast is $30.0, which is an increase of 39.41% from the latest price.

Price Target
$30.0
(39.41% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Spyre Therapeutics Announces Grants of Inducement Awards

WALTHAM, Mass. , Dec. 22, 2023 /PRNewswire/ -- Spyre Therapeutics, Inc. ("Spyre") (NASDAQ: SYRE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to transform ...

9 days ago - PRNewsWire

Spyre Therapeutics Announces $180 Million Private Placement

WALTHAM, Mass. , Dec. 7, 2023 /PRNewswire/ -- Spyre Therapeutics, Inc. ("Spyre") (NASDAQ: SYRE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to transform t...

24 days ago - PRNewsWire

Aeglea BioTherapeutics Announces Name Change to Spyre Therapeutics, Appoints CEO and Additional Directors, and Expands Leadership Team to Develop Next-Generation Therapeutic Combinations for the Treatment of IBD

Company will begin trading on Nasdaq under trading symbol "SYRE" effective November 28, 2023 Biotechnology leader Cameron Turtle, DPhil, appointed as Chief Executive Officer and Member of the Board of...

4 weeks ago - PRNewsWire

Aeglea BioTherapeutics Announces Grants of Inducement Awards

WALTHAM, Mass. , Nov. 22, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (NASDAQ: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to trans...

5 weeks ago - PRNewsWire

Aeglea BioTherapeutics Reports Third Quarter 2023 Financial Results and Provides Corporate Update

Continued progress across the Company's potentially best-in-class inflammatory bowel disease (IBD) portfolio SPY001, a half-life extended anti-α4β7 antibody, is on track for an expected IND filing in ...

7 weeks ago - PRNewsWire

SHAREHOLDER ALERT: Purcell & Lefkowitz LLP Announces Shareholder Investigation of Aeglea BioTherapeutics (NASDAQ: AGLE)

NEW YORK , Nov. 1, 2023 /PRNewswire/ -- Purcell & Lefkowitz LLP announces that it is investigating Aeglea BioTherapeutics, Inc. (NASDAQ: AGLE) on behalf of the company's shareholders.  The investigati...

2 months ago - PRNewsWire

Aeglea BioTherapeutics to Participate in Upcoming November Investor Conferences

WALTHAM, Mass. , Oct. 30, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (Nasdaq: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to trans...

2 months ago - PRNewsWire

Aeglea BioTherapeutics to Participate in Upcoming September Conference

WALTHAM, Mass. , Sept. 14, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (Nasdaq: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to tran...

3 months ago - PRNewsWire

Aeglea BioTherapeutics Announces Reverse Stock Split

WALTHAM, Mass. , Sept. 7, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (Nasdaq: AGLE), a biotechnology company advancing a pipeline of antibody therapeutics with the potential to trans...

4 months ago - PRNewsWire

Aeglea BioTherapeutics Expands Executive Leadership Team with Appointment of Industry Veterans Scott Burrows and Heidy Abreu King-Jones

Scott Burrows, former Arcutis Biotherapeutics CFO, assumes role as Chief Financial Officer  Heidy Abreu King-Jones, former Provention Bio CLO & Corporate Secretary, assumes role as Chief Legal Officer...

Other symbols: ARQT
4 months ago - PRNewsWire

Aeglea BioTherapeutics Reports Second Quarter 2023 Financial Results

Acquisition of Spyre's assets and concurrent oversubscribed $210.0 million private investment positions the company to advance a potentially best-in-class inflammatory bowel disease (IBD) portfolio, i...

5 months ago - PRNewsWire

Polar Capital Holdings Plc Enters Stake in Aeglea BioTherapeutics Inc

On July 19, 2023, Polar Capital Holdings Plc (Trades, Portfolio), a London-based investment firm, made a significant move in the biotechnology sector by investing in 3,936,198 shares in Aeglea BioTher...

5 months ago - GuruFocus

Aeglea BioTherapeutics Announces Sale of Pegzilarginase to Immedica Pharma

Global rights to pegzilarginase in development for Arginase 1 Deficiency sold to Immedica Pharma for $15 million upfront cash proceeds and up to $100 million of contingent milestone payments Marketing...

5 months ago - PRNewsWire

Aeglea BioTherapeutics Announces Grant of Inducement Awards

AUSTIN, Texas and WALTHAM, Mass. , June 23, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. ("Aeglea") (NASDAQ: AGLE) today announced that, in connection with the acquisition of Spyre Therapeutics, ...

6 months ago - PRNewsWire

Aeglea BioTherapeutics Announces Acquisition of Spyre Therapeutics

Acquisition of Spyre and concurrent oversubscribed $210 million private investment positions the company to advance a leading inflammatory bowel disease (IBD) portfolio Spyre, the second spinout from ...

6 months ago - PRNewsWire

Aeglea BioTherapeutics Reports First Quarter 2023 Financial Results

$39.8 million of cash and cash equivalents, marketable securities, and restricted cash as of March 31, 2023 AUSTIN, Texas , May 11, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE) toda...

8 months ago - PRNewsWire

Aeglea BioTherapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

AUSTIN, Texas , March 17, 2023 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), a clinical-stage biotechnology company developing a new generation of human enzyme therapeutics as innovative...

10 months ago - PRNewsWire

Aeglea BioTherapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Program Updates

Jeffrey Goldberg, experienced biotech executive, appointed president and CEO; further strengthened senior management team with appointments of chief medical officer and chief product officer $57.3 mil...

10 months ago - PRNewsWire

Aeglea BioTherapeutics Announces Update to Corporate Structure to Increase Operational Efficiency

Streamlining of organization to focus on near-term deliverables for pegtarviliase in Homocystinuria and long-term value creation Cortney Caudill, M.B.A., has been promoted to the newly created role of...

1 year ago - PRNewsWire

Aeglea BioTherapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

AUSTIN, Texas, Dec. 2, 2022 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), a clinical-stage biotechnology company developing a new generation of human enzyme therapeutics as innovative so...

1 year ago - PRNewsWire

Aeglea BioTherapeutics Appoints Jeffrey M. Goldberg as Chief Executive Officer

AUSTIN, Texas , Nov. 30, 2022 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), a clinical-stage biotechnology company developing a new generation of human enzyme therapeutics as innovative ...

1 year ago - PRNewsWire

Aeglea BioTherapeutics Appoints Linda Neuman, M.D., M.B.A, to Chief Medical Officer

AUSTIN, Texas , Nov. 15, 2022 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. (NASDAQ: AGLE), a clinical-stage biotechnology company developing a new generation of human enzyme therapeutics as innovative...

1 year ago - PRNewsWire

Aeglea BioTherapeutics Reports Third Quarter 2022 Financial Results and Provides Program Updates

Interim Clinical Data from Phase 1/2 Trial of Pegtarviliase Expected in Fourth Quarter of 2022; Currently Dosing Cohort 3 at 1.35 mg/kg MAA for Pegzilarginase for the Treatment of Arginase 1 Deficienc...

1 year ago - PRNewsWire

Aeglea BioTherapeutics Hosting Key Opinion Leader Webinar on Classical Homocystinuria and Pegtarviliase's Potential Role in Treatment

Event to be Held Thursday, October 27 th at 10 AM ET AUSTIN, Texas , Oct. 19, 2022 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. (NASDAQ: AGLE), a clinical-stage biotechnology company developing a new ...

1 year ago - PRNewsWire

Aeglea BioTherapeutics Provides Clinical Progress and Regulatory Update for Homocystinuria Program

AUSTIN, Texas , Oct. 4, 2022 /PRNewswire/ -- Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), a clinical-stage biotechnology company developing a new generation of human enzyme therapeutics as innovative s...

1 year ago - PRNewsWire